Following the boom-bust rollercoaster just like local tech workers and the original forty niners, coach Jim Harbaugh (who is from Palo Alto and coached Stanford previously) seems to be leading the niners out of the lean times, even if they haven't returned to the golden era of Montana, Rice, Lott, Young, Walsh, et al :)
Windy Candlestick Park is south (and east) of most SF destinations, but readily accessible by the Muni T line - although, it's starting to look like the niners may be heading south for warmer (and richer) pastures.
Address: Candlestick Park, SF
Website: http://www.49ers.com/