The oldest building in San Francisco, Mission Dolores de Asis still holds mass and provides visitors a window into the native Ohlone culture (at least, the end of it), and Spanish colonization of San Francisco, with still-working bells.
Nearby Dolores Park and Bi-Rite Creamery - not to mention the rest of the Mission District - provide more earthly nourishment.
Address: 3321 16th St, SF, CA
Website: http://www.missiondolores.org/
Wikipedia: http://en.wikipedia.org/wiki/Mission_San_Francisco_de_As?